Saturday, July 30, 2011

Skin Rash in Pregnancy - Impetigo Herpetiformis

Skin rash is defined as a condition of skin change of the color and appearance and can be localized or affected the whole body. Skin rashes during pregnancy can be normal or abnormal, in some cases it can have a negative health affects to the mother and fetus. If you are experience certain itching with or without rash, please consult with your doctor as soon as possible.

There are some common types of skin rash in pregnancy, including
1. Impetigo Herpetiformis
Impetigo Herpetiformis is a rare form of severe pustular psoriasis and happened mostly in the in the second half of pregnancy. The rash usually starts with groins, armpits and folds of elbows and knees and resolves after delivery but can recur in subsequent pregnancies.

2. Symptoms
a. Appear in clusters of pus-filled blisters in spiral-shape
b. Blisters disappear after a few days,then followed by the new blisters around the edge
c. The cycle repeated as the diseases progress.
In serve cases, it may cause
c.1. Fever
c.2. Chills
c.3. Nausea
c.4. Vomiting
c.5. Diarrhea
c.6. Tetany
c.7. Loose stools
c.8. Hair loss
c.9. Etc.

Causes and risk factor
1. Doctors disagree about whether impetigo herpetiformis is a distinct disease caused by pregnancy or a form of pustular psoriasis triggered by pregnancy, acccording to Impetigo Herpetiformis -A rare dermatosis of pregnancy associated prenetal complications by K.S. Lim, MBBS, MRCP (UK), MBY Tang MBBS, MRCP (UK), M. Med (Int. Med), PPL Ng MBBS, MRCP (UK), the authors indicated while the underlining etiology and pathogenesis of IH is still unkown, there is some debate as to whether this a distinct dermatosis of pregnancy or a form of pustular psoriasis,...
2. Personal or family history of psoriasis
Increased risk of Impetigo Herpetiformis in pregancy if a woman has personal or family history of psoriasis.
3. Etc.

Treatments
Since in long-standing disease, placental insufficiency may lead to stillbirth, neonatal death of the child or fetal abnormalities, if you have the above symptoms, please check with your doctor immediately. Early diagnosis, and intensive treatment is absolutely necessary. Some doctors recomemend the intake of adrenocorticotrophic hormone.
According to the study of Impetigo herpetiformis: A case report and review of literature by Felix BB Yap, MRCP (UK), researchers found that Impetigo herpetiformis can usually be successfully treated with topical and systemic corticosteroids. Antibiotics may be indicated for secondary bacterial infection. Fluid and electrolytes especially calcium should be monitored and normalized. Unresponsive cases can be given cyclosporine, narrowband ultraviolet B (NBUVB), psoralen ultraviolet A (PUVA), clofazimine or induction of early delivery. During the postpartum period, oral retinoid can be given. Treatment is imperative due to the life threatening nature of the disease.


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